MPH5302 - Formulation and Evaluation of Research Objectives - Assessment 2

• Alignment with Learning Outcomes (LO): Please see the Assessment 2 E-book
• General Instructions: Please see the Appendix and Assessment 2 E-book
• Instructions for Submission: Please see the Assessment 2 E-book
• Marking Criteria: Please see the Assessment 2 E-book
• Required Data: Please find the data files “CVD-Data” and “DBP-Data” in the “Assessment 2” section on the moodle Required access to IBM SPSS to open these data files.
• Returning date: Please see the Assessment 2 E-book
• Please don’t post any discussions related to the AT2 questions/answers on Discussion Violation of this request may affect your grade in AT2.
• In case, you need any clarification on any questions please feel free to post your query on “Forum, Ask Your Instructor” with a proper

Data Description (CVD-Data): Consider a study where twelve baseline variables (e.g., age, gender, weight, BMI, etc.) among others were collected from each of the 1429 participants. Out of the 1429 participants, 952 had a history of being treated with Drug-X on a regular basis. The objective of the study was to investigate whether Drug-X was protective for various risk factors of cerebrovascular vascular disease (CVD). The participants were then followed for 5 years and their mortality status was recorded. The short and long names of the variables are given in Table 1. Note: Baseline Variable is collected at the beginning of a study.

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Table 1: Variable description for the study

Question 1 [5 marks]: Consider that an investigator aims to assess whether ‘Drug-X’ was protective for ‘mortality’ in the study sample. Evaluate the investigator’s aim by presenting the related data on an appropriate graph (Hint: no additional summary statistics or significance test required for answering this question).

Question 2 [35 marks]: Using appropriate statistical method(s) investigate whether patients who had a history of being treated with Drug-X on a regular basis have significantly different systolic blood pressure (SBP), diastolic blood pressure (DBP) and cholesterol level (CHL) compared to patients without Drug-X treated.

Question 3 [20 marks]: Using appropriate statistical methods evaluate the significance of difference of CHL and SBP between the BMI categories.

Question 4 [20 marks]: Using appropriate statistical methods compare patients’ SBP and DBP by STROKE status.  Hint: Statistical significance test required.

Question 5 [15 marks]: In a clinical trial, 35 subjects were treated with a new drug to show the efficacy of the drug in reducing diastolic blood pressure (DBP). Their blood pressure was observed before the treatment and after 10 weeks of the treatment (see the DBP-data on the Moodle site). Using appropriate statistical method(s) evaluate whether the drug is significantly effective.

Question 6 [5 marks]: State the learning outcomes of Modules 4-7 and describe how this assessment is aligned with these learning outcomes (maximum of 150 words, this will be excluded from the total word count of this assessment).

 Appendix:                                                                                                                                     

This assignment covers Modules 1-7 of this unit for data analysis. All questions must be answered using the statistical methods from Modules 1-7.

The study description, questions and a dataset for this assessment will be made available two weeks prior to the due date.

You can use IBM SPSS software for data analysis. Or you can use any other statistical software package that will allow you to import and analyse the given .sav data files.

In a SINGLE Word document, your report must:

• Have a title page, which includes your full name and student ID, and the title of the assessment;
• Have a content page, which lists the content of your report;

·         Tips apply for questions 1-5 in AT2:

• State the objectives and hypothesis (if any) of the study and justify the use of the selected statistical method/s to evaluate it;
• Address all key issues related to the chosen statistical methods;
• Analyse the given data using a statistical software package such as IBM SPSS;
• Use "Copy and Paste Special" or "Snipping Tool" to copy the appropriate results from the SPSS output to word document;
• Discuss the results in the context of the study question/hypothesis;
• Provide a summary conclusion/impact of findings in the context of the research question;
• Evidence of originality and insight is expected throughout the presentation;
• In case, you are analysing multiple variables for a question, please combine all these variables in each steps/sections in the presentation;
• Present the answer of each question separately;

• Have an appendix for all relevant data analysis
• A clear and logical presentation is strongly

·         Please read marking criteria/rubric

 Important information                                                                                                                  

• The 2500 word limit does not include the content page, tables, graphs or
• Your report must be formatted in A4 size (210 x 297 mm), with Times New Roman, size 12 font.
• Name your file with your file name and the assessment number: lastname-firstname-
• Your report must not be longer than 25 pages. If you have any more than that, only the first 25 pages will be
• All important analysis output must be added as an appendix, with table/graph number and a proper
• You must combine all the information into a SINGLE Word (.docx) file, as you will only be able to make one submission to the assessment dropbox. For full information about submission, see the "Submission details and feedback" page later in this book.
• You must not copy and paste information from the internet. If you do use internet information, please put it in your own words. References may not be required, but if you do use them, you must cite all of your sources using the Vancouver referencing style.
• This assessment is worth 30%. It will be marked as a percentage of 100.